LISI GROUP - Integrated report 2022

THE MAIN DEVELOPMENT ORIENTATIONS Respond to the developments of minimally invasive surgery The development of day surgery, which is growing rapidly in the US and is being rolled out in Europe, is accelerating the expansion of minimally invasive surgery product lines. LISI MEDICAL supports its customers in this phase of market development by adjusting its production capacities to the development of programs launched during the COVID period. Accelerate the development of implants France / United States The LISI MEDICAL division has initiated joint development programs for specific implants and devices between the Neyron site, in France, and the US plant in Big Lake, Minnesota. These cross- developments, carried out for major contractors, constitute a strong axis of development for LISI MEDICAL. OUR 3 LINES OF BUSINESS UNDERSTANDING LISI SPINAL AND TRAUMA IMPLANTS 11 % OF THE DIVISION’S SALES The range of spinal implants and traumatology covers indications for the treatment of trauma or bone deformities (connectors, screws, plate, etc.) RECONSTRUCTION IMPLANTS 34 % OF THE DIVISION’S SALES The product range covers orthopedic joint replacement implants (hip, knee, shoulder). z Hip z Knee z Shoulder z Traumatology plate z Pedicle screws and Connectors 17 LISI – 2022 INTEGRATED REPORT

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